منابع مشابه
Gastrointestinal urease in man ' Part I Activity of mucosal urease
The relationship postulated between hepatic coma and hyperammonaemia implicates the gastrointestinal tract as a major source of the excess ammonia in the peripheral blood of some patients with cirrhosis (Butt and Summerskill, 1961; Chalmers, 1960; Sherlock, Summerskill, White, and Phear, 1954). Conventional therapy, comprising protein restriction, antibiotics, and enemas, is directed toward eli...
متن کاملStudies on Crystalline Urease
1. Crystalline urease is not inactivated by trypsin in the absence of a gum. In fact, the presence of trypsin alone in aqueous solutions of urease has an action similar to that of gum, that is, it acts as a "protective colloid" for urease. 2. Crystalline urease is inactivated by trypsin in the presence of a gum. This occurs with great rapidity if purified (crystalline) trypsin is used. 3. If tr...
متن کاملUrease inhibitors: A review
Urease inhibitors possess a wide application in agriculture, clinical science and understanding of enzyme kinetics. These inhibitors play a significant role in reducing the loss of nitrogen from urea fertilizer in the form of volatile ammonia and, thus, improve the utility of urea based fertilizers. Their impact as an effective drug against urease producing bacterial infection is well documente...
متن کاملThe Activation of Urease
1. It has been shown that the activity of solutions of twice recrystallized urease is reversibly increased by moderate heating and reversibly decreased by storage in the cold, even in the frozen state. 2. Crude extracts of jack bean meal containing potent urease undergo this same type of reversible activation by heating and inactivation by cooling. Dilution has the same potentiating effect on t...
متن کامل10 Urease Inhibition Muhammad
The design, synthesis, characterization and exploring the broad spectrum of potency of biologically active molecular building blocks have attracted the attention of scientific community since last couple of decades. The emergence of pathogenic resistance is a natural phenomenon and investigations toward the advances of new structurally diverse inhibitors have always been at the esteem of pharma...
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ژورنال
عنوان ژورنال: The Lancet
سال: 1916
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(00)53305-4